1"Bhikkhus, there are these four knots. What four?
The bodily knot of covetousness,
the bodily knot of ill will,
the bodily knot of distorted grasp of rules and vows,
the bodily knot of adherence to dogmatic assertion of truth.[n.47] Spk explains "bodily knot" (kaāyagantha) as a knot in the name-body (nāmakāya), a defilement which knots and connects (ganthanaghaṭanakilesa). Spk-pṭ: A defilement which produces connection, bondage, known as the binding to suffering through the connection of cause with effect, of the round of kamma with the round of results. The fourth knot, idaṁsaccābhinivesa kāyagantha, is literally "the bodily knot of adherence to (the view) ‘This (alone) is truth.’" sn.v.60
These are the four knots.

The Noble Eightfold Path is to be developed
- for direct knowledge of these four knots,
- for the full understanding of them,
- for their utter destruction,
- for their abandoning.

What Noble Eightfold Path?
Here, bhikkhus, a bhikkhu develops right view, right intention, right speech, right action, right livelihood, right effort, right mindfulness, right concentration,
- which is based upon seclusion, dispassion, and cessation, maturing in release;
- which has as its final goal the removal of lust, the removal of hatred, the removal of delusion;
- which has the Deathless as its ground, the Deathless as its destination, the Deathless as its final goal;
- which slants, slopes, and inclines towards Nibbāna.

This Noble Eightfold Path is to be developed
- for direct knowledge of these four knots,
- for the full understanding of them,
- for their utter destruction,
- for their abandoning."

This sutta may be fully expanded in accordance with the fourfold method employed in SN45.161.

1"Cattārome, bhikkhave, ganthā. Katame cattāro?
Abhijjhā kāyagantho, byāpādo kāyagantho, sīlabbataparāmāso kāyagantho, idaṁsaccābhiniveso kāyagantho – ime kho, bhikkhave, cattāro ganthā.

Imesaṁ kho, bhikkhave, catunnaṁ ganthānaṁ abhiññāya pariññāya parikkhayāya pahānāya … pe …

ayaṁ ariyo aṭṭhaṅgiko maggo bhāvetabbo"ti.

Catutthaṁ.